Thermo Fisher Scientific Desmoglein 1 Monoclonal Antibody (27B2)
Thermo Fisher Scientific의 Desmoglein 1 Monoclonal Antibody (27B2)는 인간 Desmoglein-1을 타겟으로 하는 Mouse IgG1 항체입니다. Western blot, IHC, ICC, Flow Cytometry 등 다양한 응용에 적합하며, 단백질 A로 정제된 액상 형태로 제공됩니다. 연구용 전용 제품입니다.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–3 µg/mL | View 4 publications |
| Immunohistochemistry (IHC) | – | View 4 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:10–1:100 | View 1 publication |
| Immunohistochemistry (Frozen) (IHC (F)) | 20–50 µg/mL | View 1 publication |
| Immunocytochemistry (ICC/IF) | – | View 4 publications |
| Flow Cytometry (Flow) | – | View 2 publications |
| Immunoprecipitation (IP) | 5–10 µg | View 1 publication |
| Miscellaneous PubMed (Misc) | – | View 4 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Bovine, Horse, Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 27B2 |
| Immunogen | Human desmoglein-1 intracellular domain |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.1% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2533088 |
Target Information
Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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