
Thermo Fisher Scientific FUS Monoclonal Antibody (1FU-1D2)
FUS 단백질을 인식하는 마우스 단클론 항체로 Western blot, ICC/IF, IP에 적합. 합성 펩타이드 면역원 사용. 인간 시료에서 FUS/TLS(~70kDa) 검출. 액상 형태, 나트륨 아지드 포함, -20°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:5,000 | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:1,000 | View 1 publication |
| Immunoprecipitation (IP) | - | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1FU-1D2 |
| Immunogen | Synthetic peptide (GPRDQGSRHDSEQDNSDC) coupled to ovalbumin. From aa 266 to aa 283 of FUS. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Ascites |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2633334 |
Product Specific Information
- MA3-089 detects AID from human samples.
- Successfully used in Western blot.
- Immunogen: synthetic peptide coupled to ovalbumin, aa 266–283.
- Detects FUS/TLS (~70 kDa) in human samples.
Target Information
This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex, which is involved in pre-mRNA splicing and mRNA export. The protein belongs to the FET family of RNA-binding proteins implicated in gene expression regulation, genomic integrity maintenance, and mRNA/microRNA processing.
Alternative splicing results in multiple transcript variants.
Defects in this gene are associated with amyotrophic lateral sclerosis type 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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