Thermo Fisher Scientific FUS Monoclonal Antibody (1FU-1D2)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:5,000

View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

1:1,000

View 1 publication 1 publication

Immunoprecipitation (IP)

-

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human

Published species

Human

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

1FU-1D2

Immunogen

Synthetic peptide (GPRDQGSRHDSEQDNSDC) coupled to ovalbumin. From aa 266 to aa 283 of FUS if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:FUS,uniProtId:P35637-1,ncbiNodeId:9606,antigenRange:266-283,antigenLength:526,antigenImageFileName:MA3-089_FUS_P35637-1_House_mouse.svg,antigenImageFileNamePDP:MA3-089_FUS_P35637-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

Conc. Not Determined

Storage buffer

ascites

Contains

0.05% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2633334

Product Specific Information

MA3-089 detects AID from human samples

MA3-089 has been successfully used in Western blot.

The MA3-089 immunogen is the synthetic peptide coupled to ovalalbumin, aa 266 to 283. MA3-089 detects FUS/TLS (~70kDa) in human samples.

Target Information

This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.