Thermo Fisher Scientific MRP7 Polyclonal Antibody
MRP7 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, Western blot에 적합하며 Human, Mouse, Rat에 반응합니다. 항원 특이적 친화 크로마토그래피로 정제된 고순도 항체로 연구용으로 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
- View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 834–887 of Human MRP7 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719130 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen, and the purity is >95% (by SDS-PAGE).
Target Information
The MRP family consists of nine ABC transporters that function as efflux pumps for structurally diverse lipophilic anions.
MRP7 (multidrug resistance-associated protein 7, ATP-binding cassette sub-family C member 10) is a multi-pass membrane protein belonging to the ABC transporter family.
It mediates ATP-dependent transport of 17β-estradiol-D-17-β-glucuronide (E217βG) and contributes to cellular detoxification via lipophilic anion extrusion.
MRP7 contains two ABC transmembrane type 1 domains and two ABC transporter domains, and likely has three isoforms. Isoform 2 is the most widely expressed, while isoform 1 is predominantly found in the spleen.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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