Thermo Fisher Scientific QRFPR Polyclonal Antibody
QRFPR 단백질을 인식하는 Thermo Fisher의 토끼 폴리클로날 항체로, Western blot 및 Immunocytochemistry에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 인간, 마우스, 랫트 반응성을 보입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 178–334 of Human QRFPR |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719135 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by epitope-specific immunogen affinity chromatography. The purity is greater than 95% as determined by SDS-PAGE.
Target Information
G protein-coupled receptors (GPRs) are a family of transmembrane receptors that transmit extracellular signals (ligand binding) into intracellular responses via G protein activation. This signaling mechanism is conserved across eukaryotes and mediates environmental sensing and cell communication.
All GPRs have seven membrane-spanning domains, with glycosylated extracellular regions containing conserved cysteine residues that form disulfide bonds to stabilize receptor structure.
GPR103, a 455 amino acid protein, shows highest expression in the brain, retina, trigeminal ganglion, hypothalamus, and vestibular nucleus. In peripheral tissues, expression is limited to the heart, kidney, and testis. GPR103 may play a role in adrenal regulation. The hypothalamic neuropeptide 26RFa acts as an endogenous ligand for GPR103.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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