
Thermo Fisher Scientific Cytokeratin 17 (KRT17) (Basal Epithelial Marker) Monoclonal Antibody (E3 (Ks17.E3))
Cytokeratin 17 단백질을 인식하는 E3 (Ks17.E3) 클론의 mouse monoclonal antibody입니다. Western blot, IHC, ICC/IF, Flow cytometry 등 다양한 응용에 적합하며, 인간 및 여러 종에 반응합니다. Protein A/G 정제, 액상 형태로 제공됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Bovine, Goat, Human, Pig, Rat |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | E3 (Ks17.E3) |
| Immunogen | Cytoskeletal fraction of rat colon epithelium |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Cytokeratins are a subfamily of intermediate filament proteins, showing considerable biochemical diversity with at least 20 distinct polypeptides in human epithelial tissues. They range in molecular weight from approximately 40 kDa to 68 kDa and have isoelectric points between 4.9 and 7.8.
Each epithelial tissue expresses specific cytokeratin patterns characteristic of its type and differentiation stage. These expression profiles are valuable in distinguishing various epithelial malignancies.
Cytokeratin antibodies are widely used in tumor differential diagnosis via immunohistochemistry, as well as in cytopathology and flow cytometric analyses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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