
Thermo Fisher Scientific Cytokeratin 16 (KRT16) (Suprabasal Keratinocyte Marker) Recombinant Rabbit Monoclonal Antibody (KRT16/2043R)
Recombinant rabbit monoclonal antibody targeting Cytokeratin 16 (KRT16), a suprabasal keratinocyte marker. Suitable for IHC applications. High purity via Protein A/G purification. Supplied as unconjugated liquid form, 1 mg/mL in PBS buffer. For researc...
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | KRT16/2043R |
| Immunogen | Recombinant fragment from the C-terminal of human Cytokeratin 16 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
KRT16 is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins arranged in pairs of heterotypic keratin chains and are clustered in a region of chromosome 17q12–q21.
This keratin has been coexpressed with keratin 14 in epithelial tissues such as esophagus, tongue, and hair follicles. Mutations in this gene are associated with type 1 pachyonychia congenita, non-epidermolytic palmoplantar keratoderma, and unilateral palmoplantar verrucous nevus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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