Thermo Fisher Scientific IFN beta Polyclonal Antibody
다양한 응용(WB, IHC, ELISA, IP, Neutralization)에 사용 가능한 IFN beta 폴리클로날 항체. 인간 및 바이러스 시료에 적합하며, Sheep 유래 Ig 폴리클로날 항체. 액상 형태로 -20°C 보관, 건빙 상태로 배송. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | Assay-dependent | - |
| Immunohistochemistry (IHC) | Assay-dependent | - |
| ELISA | Assay-dependent | View 1 publication |
| Immunoprecipitation (IP) | Assay-dependent | - |
| Neutralization (Neu) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Published species | Human, Virus |
| Host/Isotype | Sheep / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant human interferon beta 1 (Hu-IFN-beta) expressed in mammalian cells. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage conditions | -20°C |
| Shipping conditions | Dry ice |
| RRID | AB_2536277 |
Product Specific Information
Packaged by and distributed for PBL Assay Science.
Target Information
Type I Interferons (IFN-alpha/beta) are produced primarily in response to viral infection by natural IFN-producing cells (IPCs) as part of the host immune response. IFNs can also inhibit tumor development.
IFN-beta binding activates the tyrosine kinases Jak1 and Tyk2, leading to phosphorylation of STAT transcription factors and induction of immune response genes.
Several toll-like receptor (TLR) family members are known to stimulate IFN-beta production.
Clinically, IFN-beta is used for treatment of tumors, infections, and multiple sclerosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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