Thermo Fisher Scientific RASGRP3 Monoclonal Antibody (OTI3C5), TrueMAB
RASGRP3 단백질을 인식하는 고특이성 Mouse Monoclonal Antibody. Western blot에 최적화되어 있으며, Human 시료에 반응. Lyophilized 형태로 제공되어 장기 보관 가능. 연구용 신호전달 관련 단백질 분석에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3C5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 380–690 of human RASGRP3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Members of the RAS subfamily of GTPases act as GTP/GDP-regulated molecular switches in signal transduction.
Guanine nucleotide exchange factors (GEFs), such as RASGRP3, activate RAS by promoting GTP binding, linking cell surface receptors to RAS activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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