Thermo Fisher Scientific AKAP8L/HA95 Polyclonal Antibody
AKAP8L/HA95 단백질을 인식하는 Rabbit Polyclonal Antibody로 인간 시료에 반응합니다. Western blot, IHC, IP 등 다양한 응용에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며 4°C에서 보관합니다.
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Thermo Fisher Scientific AKAP8L/HA95 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:2,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 596 and 646 of human A kinase (PRKA) anchor protein 8-like (helicase A-binding protein 95 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC: Epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections.
Target Information
AKAP8L may play a role in constitutive transport element (CTE)-mediated gene expression by association with DHX9 and increase CTE-dependent nuclear unspliced mRNA export. It is proposed to target PRKACA to the nucleus and may be involved in nuclear envelope breakdown, chromatin condensation, and anchoring nuclear membranes to chromatin during cell cycle progression. It also regulates histone deacetylation during mitosis by recruiting HDAC3 and may participate in pre-mRNA splicing.
[UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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