Thermo Fisher Scientific MTA2 Polyclonal Antibody
MTA2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF에 적합하며 다양한 종에서 반응. 항원 친화 크로마토그래피로 정제된 고품질 항체로, NuRD 복합체 관련 연구에 활용 가능.
- 판매단위
- pk
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.5–2 µg/mL | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–10 µg/mL | - |
| Immunocytochemistry (ICC/IF) | 1:1,000 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues 650–700 of human MTA2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2250923 |
Product Specific Information
This antibody is predicted to react with mouse, rat, canine, bovine, and xenopus samples based on sequence homology.
Suggested positive control: Jurkat cell lysate.
Target Information
This gene encodes a protein that is a component of the NuRD (nucleosome remodeling deacetylase) complex found in the nucleus of human cells. It exhibits a broad expression pattern and is strongly expressed in many tissues.
It may be part of a small gene family involved in transcriptional regulation, either directly or indirectly through chromatin remodeling.
This protein is closely related to another family member associated with the metastatic potential of certain carcinomas, sharing domains such as DNA binding, dimerization, and methylation-related domains.
One known target protein is p53, where deacetylation correlates with loss of growth inhibition in transformed cells, linking this gene family to metastasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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