Thermo Fisher Scientific PACSIN2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.02-1 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

10 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Non-human primate, Rat, Xenopus

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide corresponding to residues 400-450 of human PACSIN 2. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PACSIN2,uniProtId:Q9UNF0-1,ncbiNodeId:9606,antigenRange:400-450,antigenLength:486,antigenImageFileName:PA1-41564_PACSIN2_Q9UNF0-1_Rabbit.svg,antigenImageFileNamePDP:PA1-41564_PACSIN2_Q9UNF0-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS with 0.2% gelatin

Contains

0.05% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2161866

Product Specific Information

This antibody is predicted to react with mouse, rat, canine, bovine, and chicken based on sequence homology.

Target Information

PACSIN 2, a 486 AA phosphoprotein is a novel member of the PACSIN family of cytoplasmic adapter proteins. It is an isoform of PACSIN with a CDC15 N-terminal domain, a C-terminal SH3 domain, 3 conserved regions specific to the PACSIN family, and 3 asn-pro-phe (NPF) motifs, which potentially bind to EH domains. This protein is known to display a ubiquitous expression pattern with the highest levels of expression in brain. Reports suggest that PACSIN 2 participates in the organization of the actin cytoskeleton, the regulation of vesicular traffic. It also participates in endocytic internalization and endocytic receptor recycling.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.