Thermo Fisher Scientific Periostin (POSTN) Monoclonal Antibody (rPOSTN/8522)
인간 Periostin 단백질을 인식하는 Mouse IgG1 단클론 항체. IHC(P) 및 IHC(PFA) 실험에 적합하며, 단백질 A/G 정제 및 무보존액 PBS 용액 형태. -20°C 보관, 연구용으로만 사용.
- 판매단위
- pk
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | rPOSTN/8522 |
| Immunogen | Recombinant fragment (around aa193–326) of human POSTN protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
Target Information
Periostin (PN), also known as osteoblast-specific factor 2 (OSF-2), is a disulfide-linked protein originally identified as an osteoblast-specific factor. It is a secreted protein that binds heparin and functions as a ligand for αVβ3 and αVβ5 integrins. In preosteoblasts, Periostin acts as a cell adhesion molecule and plays roles in osteoblast recruitment, spreading, and attachment. It is mainly detected in the lower gastrointestinal tract, aorta, stomach, placenta, uterus, and breast tissues, but is upregulated in epithelial ovarian tumors and overexpressed in breast cancer. Expression of Periostin increases with BMP2 and TGFβ1 stimulation. Structurally, it contains a signal sequence, a cysteine-rich domain, a fourfold repeated fasciclin-like domain, and a C-terminal domain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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