Thermo Fisher Scientific PYY Polyclonal Antibody, Biotin
Biotin으로 결합된 Thermo Fisher Scientific PYY Polyclonal Antibody. 인간, 마우스, 랫트 시료에서 PYY 검출에 적합. ELISA에 최적화된 사용 가능. 합성 펩타이드(aa 24–36) 면역원 기반으로 높은 특이성과 안정성 제공.
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Applications
- ELISA (ELISA)
Tested Dilution: 1:2,000–1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Chicken / IgY |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 24–36 of human PYY |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2172981 |
Product Specific Information
PA1-9589 detects PYY in human, mouse, and rat samples.
PA1-9589 has been successfully used in ELISA procedures.
The immunogen is a synthetic peptide corresponding to amino acids 24–36 (L R H Y L N L V T R Q R Y) of human PYY.
Target Information
Peptide tyrosine-tyrosine amide (3–36), or PYY (3–36), is a major metabolite of the gut hormone PYY.
It is produced by dipeptidyl peptidase IV acting on PYY in the intestinal brush border and in circulation.
PYY (3–36) is a potent inhibitor of food intake in rats and humans, acting selectively on the Y2 receptor to inhibit orexigenic NPY neurons in the arcuate nucleus, thereby disinhibiting anorexigenic POMC neurons.
The anorexigenic effect of PYY (3–36) is additive to that of the co-secreted gut hormone GLP-1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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