Thermo Fisher Scientific HSP90 alpha Recombinant Rabbit Monoclonal Antibody (SY14-06)
Recombinant rabbit monoclonal antibody targeting HSP90 alpha for WB, IHC, and ICC/IF applications. High specificity and sensitivity with lot-to-lot consistency. Suitable for human, mouse, and rat samples. Supplied as liquid form, 1 mg/mL concentration,...
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 | 1 publication |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SY14-06 |
| Immunogen | Synthetic peptide within Human Hsp90 alpha (aa 51–100) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809351 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select optimal candidates for production.
Advantages include:
- Better specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to larger rabbit immune repertoire
Target Information
Heat shock proteins (HSPs) are expressed in response to biological stress, including heat. HSP90, a 90 kDa protein, is induced under stress conditions but also abundantly expressed under non-stress conditions. It interacts with various intracellular proteins such as steroid receptors, actin, tubulin, and kinases. HSP90 is essential for maintaining structural integrity of certain steroid receptors, facilitating ligand binding during receptor activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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