Thermo Fisher Scientific CD11c Recombinant Rabbit Monoclonal Antibody (SI19-06)
Recombinant rabbit monoclonal antibody targeting human CD11c. Validated for WB and IHC (Paraffin). Provides high specificity, sensitivity, and lot-to-lot consistency. Suitable for research use only.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:400–1:1000 |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SI19-06 |
| Immunogen | Synthetic peptide within Human CD11c aa 1,114–1,163 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809356 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. These systems clone specific antibody DNA sequences from immunoreactive rabbits, and individual clones are screened for optimal performance.
Advantages include:
- Improved specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to the rabbit immune repertoire
Target Information
CD11, along with CD18, forms a heterodimer adhesion molecule.
- CD11a: Expressed in B and T lymphocytes, macrophages, monocytes, neutrophils, basophils, and eosinophils.
- CD11b: Found in monocytes, macrophages, natural killer cells, some B and T-cells, and granulocytes.
- CD11c: Expressed in monocytes, macrophages, natural killer cells, some granulocytes, and a subset of lymphocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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