Thermo Fisher Scientific HSP90 beta Recombinant Rabbit Monoclonal Antibody (SY46-01)
HSP90 beta 단백질을 인식하는 토끼 단클론 항체로, Western blot, IHC, ICC/IF, Flow Cytometry에 적합합니다. 재조합 항체로 높은 특이도와 로트 간 일관성을 제공합니다. 단백질 A 정제, 1 mg/mL 농도의 액상 형태로 제공되며 연구용으로만 사용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| Flow Cytometry (Flow) | 1:50–1:100 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SY46-01 |
| Immunogen | Recombinant protein within Human Hsp90 beta (aa 485–724) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809350 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. These systems clone specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.
Advantages include:
- High specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to the large rabbit immune repertoire
Target Information
Heat shock proteins (HSP) are expressed in response to various biological stresses, including heat. HSP90 is a 90 kDa protein induced under stress conditions and is one of the most abundant cellular proteins under normal conditions.
HSP90 proteins are highly conserved molecular chaperones involved in:
- Signal transduction
- Protein folding and degradation
- Morphologic evolution
They associate with cochaperones and stabilize or refold denatured proteins after stress. HSP90 interacts with several intracellular proteins, including steroid receptors, actin, tubulin, aryl hydrocarbon (Ah) receptor, and kinases.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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