Thermo Fisher Scientific PLS3 Monoclonal Antibody (GT3310)
PLS3 단백질을 특이적으로 인식하는 Mouse monoclonal antibody. Western blot, IHC, ICC/IF에 적합. Human, Mouse, Rat 반응성. 단백질 A 정제, PBS 용액 형태. 연구용으로 세포 내 아폽토시스 관련 연구에 활용 가능.
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Applications 및 권장 희석 배수
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | GT3310 |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human T-Plastin (exact sequence proprietary) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.39 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2735322 |
Product Specific Information
- Positive Control: 293T, A431, HeLa
- Predicted Reactivity: Zebrafish (89%), Xenopus laevis (91%), Chicken (95%), Rhesus Monkey (100%), Bovine (99%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Phospholipid scramblases (PLS) are involved in bidirectional translocation of phospholipids between the inner and outer leaflets of the plasma membrane and play a role in apoptosis. PLS1 and PLS3 are substrates of Protein kinase C (PKC) delta and are phosphorylated by PKC-delta during apoptosis. PKC-delta translocates to mitochondria during apoptosis and phosphorylates PLS3. Overexpression of PLS3 in HEK293 cells enhances apoptosis induced by UV irradiation.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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