Thermo Fisher Scientific Phospho-S6 (Ser235) Monoclonal Antibody (GT829)
Phospho-S6 (Ser235) 단일클론 항체로, 인간 및 생쥐 시료에서 인산화된 S6 단백질 검출에 적합합니다. Western blot에 최적화되어 있으며, 단백질 합성 조절 연구에 유용합니다. Protein G 정제, 1 mg/mL 농도, PBS 용액 형태로 제공됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | GT829 |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human RPS6 (phospho Ser235). The exact sequence is proprietary. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2735319 |
Product Specific Information
- Positive Control: C8D30, Raw264.7, C2C12, 293T (20% FBS treatment for 0.5 hr)
- Predicted Reactivity: Rat (100%), Zebrafish (100%), Xenopus laevis (100%), Dog (100%), Chicken (100%), Bovine (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Ribosomes are organelles that catalyze protein synthesis, consisting of a small 40S subunit and a large 60S subunit. These subunits are composed of 4 RNA species and approximately 80 distinct proteins. The encoded cytoplasmic ribosomal protein is a component of the 40S subunit and belongs to the S6E family. It is a major substrate of ribosomal protein kinases, with phosphorylation at several C-terminal serine residues induced by growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs during growth arrest. This protein plays a role in controlling cell growth and proliferation through selective translation of specific mRNA classes. Multiple processed pseudogenes of this gene exist throughout the genome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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