Thermo Fisher Scientific Phospho-PDGFRB (Tyr1009) Monoclonal Antibody (F.812.7)
Human 및 Mouse 반응성의 Phospho-PDGFRB (Tyr1009) 단일클론 항체로, Western blot과 Immunoprecipitation에 적합합니다. Rabbit IgG 기반으로 액상 형태이며, 친화 크로마토그래피로 정제되었습니다. 세포 신호전달 연구용으로 권장됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Immunoprecipitation (IP)
- Tested Dilution: 1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | F.812.7 |
| Immunogen | Synthetic phosphopeptide corresponding to residues surrounding pTyr1009 of human PDGF receptor β |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
| Contains | <0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_10984579 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
PDGFRB is a receptor tyrosine kinase implicated in atherogenesis and cell transformation by the SIS oncogene. These growth factors act as mitogens for mesenchymal cells. The receptor’s ligand determines whether it forms homodimers or heterodimers with PDGF receptor alpha.
The PDGFRB gene is located on chromosome 5 near GM-CSF and CSF receptor genes, all associated with 5-q syndrome.
A translocation between chromosomes 5 and 12 that fuses PDGFRB (CD140b) with ETV6 leads to chronic myeloproliferative disorder with eosinophilia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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