Thermo Fisher Scientific GIPR Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

16 µg/mL

-

Immunocytochemistry (ICC/IF)

5 µg/mL

-

Product Specifications

Species Reactivity

Bovine, Dog, Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic 17 amino acid peptide from N-terminal extracellular domain of human GIPR. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GIPR,uniProtId:P48546-1,ncbiNodeId:9606,antigenRange:1,antigenLength:466,antigenImageFileName:PA5-33585_GIPR_P48546-1_Rabbit.svg,antigenImageFileNamePDP:PA5-33585_GIPR_P48546-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS

Contains

0.1% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2550965

Product Specific Information

BLAST analysis of the peptide immunogen showed 100% homology with human protein GHRHR.

Percent identity with other species by BLAST analysis: Human, Gorilla, Bovine, Dog, Panda (100%) Horse, Rabbit (94%) Marmoset, Hamster (88%) Rat (82%).

Target Information

GIPR encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP), which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in this gene thus may contribute to the pathogenesis of diabetes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.