Thermo Fisher Scientific CD200R Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

• In direct ELISAs and Western blots, less than 5% cross-reactivity with recombinant mouse CD200 R1 is observed.
• Reconstitute at 0.2 mg/mL in sterile PBS.
• Endotoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.

Target Information

CD200R (OX2R) is a receptor for the OX-2 membrane glycoprotein, and both the receptor and substrate are cell surface glycoproteins containing two immunoglobulin-like domains.
CD200R is restricted to the surfaces of myeloid lineage cells and may function as a myeloid downregulatory signal.
In mouse, CD200R is expressed primarily by peripheral blood monocytes and neutrophils, as well as other leukocytes including T-lymphocytes and mast cells.
Alternative splicing of CD200R results in multiple transcript variants. Diseases associated with CD200R dysfunction include primary hypertrophic osteoarthropathy.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.