Thermo Fisher Scientific CD9 Monoclonal Antibody (EM-04), FITC

Applications

• Flow Cytometry (Flow): 2–4 µg/mL

Product Specifications

Available Formats

• Unconjugated (MA1-10309)
• APC (MA1-10310)
• PE (MA1-10312)
• Custom conjugation available upon request

Product Specific Information

This antibody recognizes an extracellular epitope of the CD9 antigen, a 24 kDa transmembrane protein expressed on platelets, monocytes, pre-B lymphocytes, granulocytes, and activated T lymphocytes.

Target Information

CD9 antigen is a glycoprotein expressed on developing B lymphocytes, platelets, monocytes, eosinophils, basophils, stimulated T lymphocytes, neurons, and glial cells. It belongs to the tetraspanin family, which crosses the membrane four times.
In pre-B cells and platelets, CD9 regulates activation and aggregation, possibly via integrin CD41/CD61 association.
CD9 is involved in multiple cellular processes such as motility, osteoclastogenesis, neurite outgrowth, myotube formation, sperm-egg fusion, attachment, and proliferation. It is essential for MHC II molecule association on dendritic cells, aiding T cell stimulation.
CD9 expression plays a significant role in suppressing cancer cell motility and metastasis and is considered a metastasis suppressor in solid tumors.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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