Thermo Fisher Scientific C-Peptide Monoclonal Antibody (C-PEP-01), Biotin
인간 C-펩타이드에 특이적으로 반응하는 단일클론 항체로, 바이오틴으로 표지됨. ELISA, IHC, ICC/IF, RIA 등 다양한 면역 분석에 적합. 인슐린과 교차 반응하지 않으며 높은 특이성과 안정성을 제공. 연구용으로만 사용 가능.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunocytochemistry (ICC/IF)
- Tested Dilution: Assay-dependent
ELISA
- Tested Dilution: Assay-dependent
Radioimmune Assays (RIA)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | C-PEP-01 |
| Immunogen | Human C-peptide conjugated to bovine serum albumin |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Size-exclusion chromatography |
| Storage buffer | PBS, pH 7.4 |
| Contains | 15 mM sodium azide |
| Storage conditions | 4°C, do not freeze |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11152740 |
Additional Formats
Product Specific Information
This antibody reacts specifically with C-peptide, a part of the proinsulin molecule. Proinsulin consists of three parts: C-peptide and two long strands of amino acids (alpha and beta chains) that become linked together to form the insulin molecule. No cross-reactivity with insulin or other peptide hormones or proteins was observed.
Target Information
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides (which are covalently linked via two disulfide bonds to form insulin) and the C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. Multiple mutant alleles with phenotypic effects have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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