Thermo Fisher Scientific CRP Monoclonal Antibody (C7)
인간 CRP를 인식하는 마우스 단클론 항체(C7)로, ELISA 등 다양한 연구용 분석에 적합합니다. Ca2+ 유무에 관계없이 항원을 검출하며, 단백질 A로 정제된 액상 형태입니다. 염증 및 면역 반응 연구에 활용 가능합니다.
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Applications
- ELISA (ELISA): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | C7 |
| Immunogen | Purified human CRP |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage buffer | PBS, pH 7.4 |
| Contains | 15 mM sodium azide |
| Storage conditions | 4°C, do not freeze |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11153543 |
Additional Formats
Product Specific Information
This antibody detects the antigen both in the presence and absence (samples containing EDTA) of Ca²⁺.
Target Information
C-reactive protein (CRP) is a major cyclic, pentameric acute-phase protein composed of five identical, noncovalently bound, nonglycosylated subunits. Each subunit consists of 206 amino acids with a molecular weight of approximately 24 kDa.
CRP is produced by the liver, and its plasma concentration increases markedly during inflammatory processes. It initiates the classical complement cascade, binds to nuclear components such as chromatin and histones, and plays an essential role in innate immunity.
CRP levels can increase 100–1000 fold in response to injury, infection, or inflammation. It functions as an opsonin, an initiator of the classical complement pathway, and an activator of monocytes/macrophages. Elevated basal CRP levels are associated with increased risk of hypertension and cardiovascular diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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