Thermo Fisher Scientific CD98 Monoclonal Antibody (MEM-108), PE
인간 CD98 항원에 특이적인 Mouse IgG1 단클론 항체로 PE 형광 표지됨. Flow cytometry에 적합하며 CD98 발현 세포 분석에 활용 가능. 액상 형태로 제공되며 4°C 암소 보관, 동결 금지.
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Applications
- Flow Cytometry (Flow): 20 µL / 1×10^6 cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MEM-108 |
| Immunogen | RAJI human Burkitt’s lymphoma cell line |
| Conjugate | PE |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE! |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11151943 |
Additional Formats
- Unconjugated
- Biotin
- FITC
- Custom conjugation available upon request
Product Specific Information
This antibody reacts with an extracellular epitope of CD98, a 125 kDa disulfide-linked heterodimer (80 kDa glycosylated heavy chain + 45 kDa non-glycosylated light chain).
CD98 is expressed on T lymphocytes (upon activation) and activated NK cells; it is also present at low levels on B lymphocytes, NK cells, monocytes, and platelets.
Target Information
CD98 (4F2) is a type II transmembrane glycoprotein that serves as the heavy chain of heterodimeric amino acid transporters (HATs).
CD98, linked to various light chains by disulfide bonds, is responsible for cell surface expression and basolateral localization of this transporter complex in polarized epithelial cells.
It interacts with β1 integrins and increases their affinity for ligands.
Beyond its role in amino acid transport, CD98 is involved in cell fusion and activation, and implicated in regulation of cellular differentiation, growth, and apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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