Thermo Fisher Scientific Human R-Spondin-3 Recombinant Protein, PeproTech
인간 R-Spondin-3 재조합 단백질로 Wnt/β-catenin 신호 조절 연구에 사용됩니다. CHO 세포 발현 시스템에서 생산되었으며, ≥95% 순도와 낮은 엔도톡신 수준을 가집니다. BMP-2 매개 세포 분화 활성 검증 완료. 동결건조 형태로 제공되며 실온 배송, -20°C 보관.
- 카탈로그번호
- 120-44-xxx (6개 옵션)
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
6개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Human R-Spondin-3 Recombinant Protein, PeproTech
Applications
Functional Assay (Functional)
- Assay-dependent
In vitro Assay (IV)
- Refer to 3 related publications
Miscellaneous PubMed (Misc)
- Refer to 2 related publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Human |
| Published species | Human, Mouse, Xenopus |
| Expression System | CHO cells |
| Amino Acid Sequence | MHPNVSQGCQ GGCATCSDYN GCLSCKPRLF FALERIGMKQ IGVCLSSCPS GYYGTRYPDI NKCTKCKADC DTCFNKNFCT KCKSGFYLHL GKCLDNCPEG LEANNHTMEC VSIVHCEVSE WNPWSPCTKK GKTCGFKRGT ETRVREIIQH PSAKGNLCPP TNETRKCTVQ RKKCQKGERG KKGRERKRKK PNKGESKEAI PDSKSLESSK EIPEQRENKQ QQKKRKVQDK QKSVSVSTVH |
| Molecular Weight | 26.9 kDa |
| Class | Recombinant |
| Type | Protein |
| Purity | ≥ 95% (SDS-PAGE & HPLC) |
| Endotoxin Concentration | <1 EU/µg |
| Activity | Enhances BMP-2-mediated differentiation of MC3T3-E1 cells (ED50: 0.8–2.0 µg/ml) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Purification | Purified |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient |
Product Specific Information
Recombinant Human R-Spondin-3 is a 26.9 kDa protein consisting of 240 amino acid residues. Due to glycosylation, it migrates at an apparent molecular weight of approximately 37.0 kDa by SDS-PAGE under reducing conditions.
This product is shipped at ambient temperature. For storage, handling, and reconstitution information, please refer to the lot-specific Certificate of Analysis.
Target Information
RSPO3 is a member of the R-spondin family and plays a role in the regulation of Wnt (wingless-type MMTV integration site family)/β-catenin and Wnt/planar cell polarity (PCP) signaling pathways. These pathways are involved in development, cell growth, and disease pathogenesis. RSPO3 regulates the balance between angioblast and blood cell specification during embryonic vasculogenesis and angiogenesis and may be involved in tumor development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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