Thermo Fisher Scientific IL-4 Monoclonal Antibody (E10022)
인간 IL-4에 특이적인 마우스 단클론 항체로 ELISA 및 Western blot에 적합. 재조합 IL-4를 면역원으로 사용하며 비결합형 형태로 제공. 고순도 Protein G 정제, 4°C 보관. 연구용으로만 사용 가능.
- 카탈로그번호
- M2IL4I
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific IL-4 Monoclonal Antibody (E10022)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| ELISA | 0.001–20 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | E10022 |
| Immunogen | Recombinant human IL-4 purified from Pichia pastoris |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.5 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 10% trehalose |
| Contains | No preservative |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_417050 |
Additional Formats
Product Specific Information
M2IL4I targets IL-4 in ELISA and Western blot applications and shows reactivity with human samples.
The immunogen is recombinant human IL-4 purified from Pichia pastoris.
Detects IL-4 with a predicted molecular weight of approximately 15 kDa.
Endotoxin levels ≤ 10 µg/mL.
Target Information
Interleukin-4 (IL-4) is a pleiotropic, immune-modulatory cytokine produced by activated T cells and serves as a ligand for the IL-4 receptor.
IL-4 interacts with IL13 via the shared receptor, contributing to overlapping cytokine functions.
STAT6 plays a key role in mediating IL-4–dependent immune regulation.
The IL-4 gene is located within the cytokine gene cluster on chromosome 5q, near IL13 and IL5, coordinated by long-range regulatory elements.
A known splice variant, IL-4 delta 2, has been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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