
Thermo Fisher Scientific MCP-1 Monoclonal Antibody (E10052)
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Applications
Tested Dilution
Publications
Western Blot (WB)
1-2 µg/mL
ELISA (ELISA)
Assay-dependent
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse / IgG1
Class
Monoclonal
Type
Antibody
Clone
E10052
Immunogen
Recombinant human MCP-1
Conjugate
Unconjugated Unconjugated Unconjugated
View additional formats
Form
Liquid
Concentration
1.00 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.2
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Dry ice
RRID
AB_844396
Product Specific Information
M2MCP1I targets MCP-1 in ELISA applications and shows reactivity with Human samples.
The M2MCP1I immunogen is recombinant human MCP-1.
M2MCP1I detects MCP-1 which has a predicted molecular weight of approximately 9 kDa.
This product has been tested for endotoxins by limulus amoebocyte lysate (LAL) assay and contains an endotoxin concentration of less than or equal to 10 endotoxin units per milligram (EU/mg).
Target Information
This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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