원본
Thermo Fisher Scientific p21 Monoclonal Antibody (WA-1)
상품 한눈에 보기
p21 단백질을 인식하는 WA-1 클론의 마우스 단클론 항체. Western blot, IHC, ICC/IF, ELISA 등 다양한 응용에 적합. 인간 및 비인간 영장류 반응성. 1 mg/mL 농도의 액상 형태로 제공되며 4°C 보관.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다회원가입 없이 바로 구매하세요
가입하지 않아도 비회원가로 구매하실 수 있습니다.
마지막 업데이트 2025. 08. 01. 오후 03:52
카탈로그 번호 · 상품 설명출고판매가담기
Thermo Fisher Scientific MA119271 p21 Monoclonal Antibody (WA-1) 100 ug pk판매 단위 pk ·
재고 확인 필요
493,700원VAT 포함 543,070원
Thermo Fisher Scientific · Thermo Fisher Scientific p21 Monoclonal Antibody (WA-1)
Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent | - |
| Immunocytochemistry (ICC/IF) | Assay-dependent | - |
| ELISA | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | WA-1 |
| Immunogen | Human p21 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1075236 |
Product Specific Information
This antibody reacts with p21 protein (Waf1, Cip1, SDI 1; intracellular antigen), a 21 kDa tumor suppressor that inhibits the activity of cyclin-dependent kinases and proliferating cell nuclear antigen (PCNA).
Target Information
Protein p21 is a tumor suppressor protein that inhibits Cyclin-dependent kinases (CDK) and is transcriptionally activated by p53. It plays a crucial role in cellular response to genotoxic stress and acts as a major transcriptional target of p53.
- In the nucleus, p21 binds and inhibits Cdk1 and Cdk2, blocking the G1/S and G2/M transitions after DNA damage to allow DNA repair.
- In the cytoplasm, p21 exerts anti-apoptotic effects by inhibiting caspase 3 and apoptotic kinases ASK1 and JNK.
- p21 exhibits dual roles in carcinogenesis, functioning both as a tumor suppressor and as an oncogene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
Thermo Fisher ScientificThermo Fisher Scientific PAG1 Monoclonal Antibody (MEM-255)637,400원VAT별도
Thermo Fisher ScientificThermo Fisher Scientific CD63 Monoclonal Antibody (MEM-259)601,200원VAT별도
Thermo Fisher ScientificThermo Fisher Scientific SIT Monoclonal Antibody (SIT-01)536,700원VAT별도
Thermo Fisher ScientificThermo Fisher Scientific CD44 Monoclonal Antibody (MEM-263)518,100원VAT별도
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.