Thermo Fisher Scientific Cytokeratin 7/17 Monoclonal Antibody (C-46)
Cytokeratin 7/17 단백질을 인식하는 Mouse Monoclonal Antibody (Clone C-46). 인간, 돼지, 소 시료에서 반응하며, WB, IHC, ICC, IP에 사용 가능. Protein A로 정제된 액상 형태, PBS buffer에 sodium azide 포함. 연구용으로만 사용.
- 카탈로그번호
- MA119045
- 판매단위
- pk
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–2 µg/mL | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 10 µg/mL | - |
| Immunocytochemistry (ICC/IF) | Assay-dependent | - |
| Immunoprecipitation (IP) | Assay-dependent | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Bovine, Human, Pig |
| Published Species | Not Applicable |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | C-46 |
| Immunogen | Cytoskeleton preparation of HeLa human cervix carcinoma cell line |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1075188 |
Product Specific Information
This antibody reacts with cytokeratin peptides 7 and 17 (54 and 46 kDa). Cytokeratins are members of the intermediate filament subfamily of intracellular proteins represented in epithelial tissues.
This antibody does not cross-react with mouse, rat, or rabbit.
Target Information
Cytokeratins are a subfamily of intermediate filament proteins characterized by biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides.
They range in molecular weight between ~40 kDa and ~68 kDa and have isoelectric pH between 4.9–7.8.
Human cytokeratins are numbered 1 to 20. Expression patterns vary depending on epithelium type and degree of differentiation.
Cytokeratin subtype expression is used in distinguishing epithelial malignancies and is valuable for differential diagnosis, cytopathology, and flow cytometry.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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