Thermo Fisher Scientific MFGE8 (Lactadherin) Monoclonal Antibody (MFG-06)
MFGE8(Lactadherin)에 특이적인 단일클론 항체로 Western blot 및 IHC(Paraffin)에 적합. 인간 유래 지방구막 항원으로 제작되었으며, 1 mg/mL 농도의 액상 비결합형 형태. 세포사멸 탐지, 상피세포 연구 및 자가면역·암 연구에 활용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: Assay-dependent
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 5–8 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MFG-06 |
| Immunogen | Human milk fat globule membrane preparation |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2142465 |
Product Specific Information
This antibody reacts with a 40–45 kDa glycoprotein in human milk fat globule membrane preparation.
Target Information
This gene encodes a preproprotein that is proteolytically processed to form multiple protein products.
The major encoded protein product, lactadherin, is a membrane glycoprotein that promotes phagocytosis of apoptotic cells.
This protein has also been implicated in wound healing, autoimmune disease, and cancer.
Lactadherin can be further processed to form a smaller cleavage product, medin, which comprises the major protein component of aortic medial amyloid (AMA).
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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