Thermo Fisher Scientific Abl2 Recombinant Rabbit Monoclonal Antibody (JF0951)
Thermo Fisher Scientific의 Abl2 Recombinant Rabbit Monoclonal Antibody (JF0951)은 인체, 마우스, 랫트 반응성을 가지며 Western blot과 유세포분석에 적합합니다. 고특이성과 일관된 로트 간 재현성을 제공하며, 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Flow Cytometry (Flow) | 1:50–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JF0951 |
| Immunogen | Synthetic peptide within Human ABL2 aa 502–552 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809778 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.
Key Advantages:
- Superior specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broad immunoreactivity due to rabbit immune repertoire
Target Information
ABL2 (Arg) is an Abl-related non-receptor protein tyrosine kinase that links cell surface receptors to cell proliferation and cytoskeletal reorganization. It encodes a member of the Abelson family of nonreceptor tyrosine protein kinases. The protein shares high similarity with ABL1, including tyrosine kinase, SH2, and SH3 domains, and plays a role in cytoskeletal rearrangements via its C-terminal F-actin and microtubule-binding sequences. ABL2 is expressed in both normal and tumor cells and is involved in translocation with the ETV6 gene in leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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