Thermo Fisher Scientific COX15 Monoclonal Antibody (2D2)
COX15 단백질을 표적으로 하는 Mouse IgG2a 단클론 항체로, Western blot 및 ELISA에 적합. 미토콘드리아 내 COX15 단백질 연구에 활용 가능. 액상 형태로 제공되며 -20°C에서 보관. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 1 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2D2 |
| Immunogen | COX15 (NP_510870, 92–152 a.a.) partial recombinant protein with GST tag (MW of GST tag = 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein:
LTESGLSMVD WHLIKEMKPP TSQEEWEAEF QRYQQFPEFK ILNHDMTLTE FKFIWYMEYS HTarget Information
The cytochrome c oxidase (COX) family of proteins functions as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane, ultimately resulting in the production of water.
The mammalian COX apoenzyme is a dimer, with each monomer consisting of 13 subunits, some mitochondrial and some nuclear.
COX15 (cytochrome c oxidase assembly protein COX15 homolog) is a 410 amino acid multi-pass mitochondrial membrane protein belonging to the COX15/ctaA family.
Existing as two alternatively spliced isoforms, COX15 is predominantly expressed in tissues with high oxidative phosphorylation activity, such as brain, heart, and muscle.
COX15 defects are associated with Leigh syndrome and cytochrome c oxidase deficiency (COX deficiency).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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