Thermo Fisher Scientific COX15 Monoclonal Antibody (2D2)

Applications

Western Blot (WB)

• Tested Dilution: 1–5 µg/mL

ELISA

• Tested Dilution: 1 ng/mL

Product Specifications

Product Specific Information

Sequence of this protein:

LTESGLSMVD WHLIKEMKPP TSQEEWEAEF QRYQQFPEFK ILNHDMTLTE FKFIWYMEYS H

Target Information

The cytochrome c oxidase (COX) family of proteins functions as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane, ultimately resulting in the production of water.
The mammalian COX apoenzyme is a dimer, with each monomer consisting of 13 subunits, some mitochondrial and some nuclear.
COX15 (cytochrome c oxidase assembly protein COX15 homolog) is a 410 amino acid multi-pass mitochondrial membrane protein belonging to the COX15/ctaA family.
Existing as two alternatively spliced isoforms, COX15 is predominantly expressed in tissues with high oxidative phosphorylation activity, such as brain, heart, and muscle.
COX15 defects are associated with Leigh syndrome and cytochrome c oxidase deficiency (COX deficiency).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.