Thermo Fisher Scientific Parvalbumin Monoclonal Antibody (C12), PerCP
Parvalbumin 단백질 검출용 PerCP 결합 단클론 항체. 인간, 생쥐, 랫트 시료에 반응하며 WB, IHC, ICC, ELISA에 사용 가능. 단백질 A로 정제된 액상 형태로 4°C 보관. 빠른 신경세포 및 근섬유 연구에 적합.
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Thermo Fisher Scientific Parvalbumin Monoclonal Antibody (C12), PerCP
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (IHC) | 1:100 |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
| ELISA | Assay-dependent |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | C12 |
| Immunogen | Synthetic peptide from full-length Rat Parvalbumin protein |
| Conjugate | PerCP |
| Excitation / Emission Max | 482 / 675 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 95.64 mM phosphate / 2.48 mM MES, pH 7.4, with 0.5 M EDTA |
| Contains | No preservative |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2932383 |
Additional Formats
Product Specific Information
A 1:500 dilution of MA5-45929 was sufficient for detection of Parvalbumin in 15 µg of Rat Brain by ECL immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.
Detects 12 kDa.
Target Information
Parvalbumin (PV) is a calcium-binding protein expressed in specific muscle fibers and fast-firing neurons. It belongs to the EF-hand protein family and plays a role in calcium decay during muscle contraction and relaxation cycles.
Parvalbumin is expressed in a subset of GABAergic interneurons, contributing to the balance between excitation and inhibition in the cortex and hippocampus.
In amyotrophic lateral sclerosis (ALS) patients, parvalbumin immunoreactivity is absent from neuron populations lost early in the disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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