Thermo Fisher Scientific AMT Monoclonal Antibody (OTI4C9), TrueMAB
Human AMT 단백질(aa 146-403)을 인식하는 Mouse IgG1 단클론 항체로 Western blot에 최적화. 무보존제, 동결건조 형태로 제공되며, 재구성 후 1 mg/mL 농도로 사용 가능. 연구용으로 글리신 절단 효소 시스템 관련 연구에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4C9 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 146–403 of human AMT produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The glycine cleavage system (EC 2.1.2.10) is a mitochondrial enzyme complex composed of four components:
- P protein: Pyridoxal phosphate-dependent glycine decarboxylase
- H protein: Lipoic acid-containing protein
- T protein: Tetrahydrofolate-requiring enzyme
- L protein: Lipoamide dehydrogenase
Defects in any of these enzymes can lead to glycine encephalopathy (GCE).
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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