Thermo Fisher Scientific MEF2D Monoclonal Antibody (OTI10B4), TrueMAB
MEF2D 단백질을 인식하는 Mouse monoclonal antibody. Western blot 및 IHC(P)에서 검증됨. Human 시료에 반응하며, carrier-free 형태로 제공. 근육 및 신경세포 분화 연구에 적합. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI10B4 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–282 of human MEF2D produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The MEF2D gene is a member of the myocyte-specific enhancer factor 2 (MEF2) family of transcription factors.
Members of this family regulate muscle and neuronal cell differentiation and development, and are modulated by class II histone deacetylases.
Fusions of MEF2D with DAZAP1 (Deleted in Azoospermia-Associated Protein 1) have been identified in acute lymphoblastic leukemia cell lines, implicating MEF2D in leukemogenesis.
This protein may also play roles in Parkinson’s disease and myotonic dystrophy.
Alternative splicing results in multiple transcript variants.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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