Thermo Fisher Scientific PDGFRA Monoclonal Antibody (OTI1A11), TrueMAB
인간 PDGFRA 단백질(aa 789-1089)에 특이적인 Mouse IgG1 단일클론 항체입니다. Western blot에 1:200~1:2,000 희석으로 사용 가능하며, 동결건조 형태로 제공됩니다. 연구용으로 kidney development 관련 PDGF 신호 연구에 적합합니다.
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Applications
- Western Blot (WB): 1:200–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1A11 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 789–1089 of human PDGFRA produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
PDGFRA (platelet-derived growth factor receptor alpha) is a cell surface receptor tyrosine kinase that binds PDGF family members, which act as mitogens for mesenchymal cells.
The receptor can form homodimers or heterodimers (with PDGFRB), depending on the bound ligand.
Knockout mouse studies show that PDGFRA is crucial for kidney development, as heterozygous mice display defective renal phenotypes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: CF807656_PDGFRA_CD140a_P16234-1_House_mouse.svg, CF807656_PDGFRA_CD140a_P16234-1_House_mouse_PDP.jpeg)
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