Thermo Fisher Scientific CHI3L1 Polyclonal Antibody
CHI3L1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF 등 다양한 응용 가능. 인간, 생쥐, 랫트 반응성 보유. 항원 친화 크로마토그래피로 정제된 고순도 항체. 연구용으로만 사용.
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Thermo Fisher Scientific CHI3L1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (IHC) | 1:50–1:200 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full length human CHI3L1 (UniProt ID: P36222-1, Range: 1–383) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2554024 |
Product Specific Information
- Detects endogenous CHI3L1 protein at a molecular weight of 43 kDa.
- Purity >95% by SDS-PAGE.
Target Information
Human cartilage glycoprotein 39 (GP-39), also known as YKL-40, is a glycoprotein secreted by articular chondrocytes, synoviocytes, and macrophages.
Serum and synovial fluid GP-39 levels are elevated in inflammatory diseases and correlate with joint destruction in rheumatoid arthritis.
GP-39 is expressed in articular chondrocytes and synovial cells, as well as in liver, but is undetectable in muscle tissues, lung, pancreas, mononuclear cells, and fibroblasts.
GP-39 is a candidate autoantigen in rheumatoid arthritis and plays an important role in cellular response to environmental changes.
For Research Use Only. Not for use in diagnostic procedures or resale without express authorization.
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