Thermo Fisher Scientific GNAO1 Polyclonal Antibody
GNAO1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot 및 IHC(P) 분석에 적합합니다. 인간, 마우스, 랫트 반응성을 가지며, 고순도 친화 크로마토그래피로 정제된 액상 형태입니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA5102620
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human GNAO1 (Accession P09471), corresponding to amino acid residues R113–I163 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852017 |
Product Specific Information
Antibody detects endogenous levels of total GNAO1.
Target Information
Heterotrimeric G proteins are membrane-bound GTPases linked to 7-TM receptors. Each G protein consists of alpha-, beta-, and gamma-subunits and is bound to GDP in the “off” state. Ligand-receptor binding activates the G protein, switching it to the “on” state and enabling Galpha activation of second messenger signaling cascades. Galphas and Galphai proteins directly bind to adenylyl cyclase to stimulate or inhibit its activity, resulting in increased or decreased cAMP levels, respectively.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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