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Thermo Fisher Scientific PSMC4 Polyclonal Antibody
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PSMC4 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot과 IHC(P) 실험에 적합합니다. 인간, 마우스, 랫트 시료에 반응하며, 액상 형태로 제공됩니다. 친화 크로마토그래피로 정제되어 고순도 신뢰성을 보장합니다.
- 카탈로그번호
- PA5102618
- 판매단위
- pk
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마지막 업데이트 2025. 08. 02. 오전 11:46
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Thermo Fisher Scientific PA5102618 PSMC4 Polyclonal Antibody 100 ul pk판매 단위 pk ·
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627,600원VAT 포함 690,360원
Thermo Fisher Scientific · Thermo Fisher Scientific PSMC4 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human PSMC4 (Accession P43686), corresponding to amino acid residues T347–K397 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2852015 |
Product Specific Information
Antibody detects endogenous levels of total PSMC4.
Target Information
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of two complexes: a 20S core and a 19S regulator.
- The 20S core consists of four rings of 28 non-identical subunits (two rings of 7 alpha subunits and two rings of 7 beta subunits).
- The 19S regulator includes a base (6 ATPase and 2 non-ATPase subunits) and a lid (up to 10 non-ATPase subunits).
Proteasomes are abundant in eukaryotic cells and cleave peptides in an ATP/ubiquitin-dependent, non-lysosomal pathway.
A modified form, the immunoproteasome, processes class I MHC peptides.
The PSMC4 gene encodes one of the ATPase subunits, part of the AAA family of ATPases with chaperone-like activity.
This subunit interacts with an orphan nuclear hormone receptor and gankyrin, a liver oncoprotein. Two transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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