Thermo Fisher Scientific UBE4A Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:5,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 797-1066 of human UBE4A (NP_001191006.1). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:UBE4A,uniProtId:Q14139-1,ncbiNodeId:9606,antigenRange:797-1066,antigenLength:1066,antigenImageFileName:PA5-120865_UBE4A_Q14139-1_Rabbit.svg,antigenImageFileNamePDP:PA5-120865_UBE4A_Q14139-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.75 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2914437

Product Specific Information

Positive test controls include: MCF7, HepG2, 293T, Mouse kidney, Mouse pancreas, Mouse liver. The target is usually found in the following locations: Cytoplasm.

Immunogen sequence: FLLDEAIQYL SKIKIQQIEK DRGEWDSLTP EARREKEAGL QMFGQLARFH NIMSNETIGT LAFLTSEIKS LFVHPFLAER IISMLNYFLQ HLVGPKMGAL KVKDFSEFDF KPQQLVSDIC TIYLNLGDEE NFCATVPKDG RSYSPTLFAQ TVRVLKKINK PGNMIMAFSN LAERIKSLAD LQQQEEETYA DACDEFLDPI MSTLMCDPVV LPSSRVTVDR STIARHLLSD QTDPFNRSPL TMDQIRPNTE LKEKIQRWLA ERKQQKEQLE

Target Information

Ubiquitination requires a ubiquitin-activating enzyme, a ubiquitin-conjugating enzyme, and usually a substrate-specific ubiquitin-protein ligase. Multiubiquitination needs a fourth factor, to bind to the ubiquitin moieties of preformed conjugates and catalyze ubiquitin chain assembly in conjunction with the first three proteins. Human protein KIAA0126, with a predicted 1,073 amino acid residues, is a member of the novel protein family defined by ubiquitination conjugation factor E4. In yeast, E4 activity is linked to cell survival under stress conditions, indicating that eucaryotes use E4-dependent proteolysis pathways for multiple cellular functions.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.