Thermo Fisher Scientific Human NPTX2 Synthetic Peptide
인간 NPTX2 단백질의 중심부 16개 아미노산 서열로 구성된 합성 펩타이드입니다. PA5-20521 항체의 차단 펩타이드로 사용 가능합니다. 순도 높은 액상 형태로 제공되며, PBS 완충액에 0.1% BSA와 0.02% sodium azide가 포함되어 있습니다. -20°C에서 보관합니다.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 16 amino acids near the center of human NPTX2.
PEP-0641 can be used as a blocking peptide with polyclonal antibody PA5-20521.
Target Information
Neuronal pentraxin (NPTX) 2 was initially identified as a member of the pentraxin family having high homology to NPTX1. Unlike NPTX1, NPTX2 is expressed in testes, pancreas, liver, heart, skeletal muscle, as well as brain. NPTX2 possesses lectin properties common to the pentraxin family, promotes neurite outgrowth, and is rapidly regulated by neuronal activity. NPTX1 and NPTX2 form heterocomplexes that contribute to both activity-independent and -dependent excitatory synaptogenesis.
Recently, NPTX2 has been found to be highly upregulated in Parkinsonian substantia nigra and localizes to Lewy bodies and Lewy neurites in sporadic Parkinson’s disease (PD), suggesting that it is involved in the pathway dysregulation that underlies PD.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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