Thermo Fisher Scientific Human ELOVL6 Synthetic Peptide

Applications

Control (Ctrl)

• Assay-dependent

Blocking Assay (BLOCK)

• Assay-dependent

Product Specifications

Product Specific Information

This peptide corresponds to 16 amino acids near the amino terminus of human ELOVL6.
PEP-0640 can be used as a blocking peptide with polyclonal antibody PA5-20520.

Target Information

Lipogenesis is a key event in the energy storage system and is controlled by the transcription factor sterol regulatory element-binding protein (SREBP)-1.
Elongation of very long chain fatty acids protein 6 (ELOVL6) is a member of the fatty acyl-CoA elongase gene family that converts palmitic to stearic acid and is a target of SREBP-1.
ELOVL6 plays an important role in de novo synthesis of long-chain saturated and monounsaturated fatty acids in conjunction with fatty acid synthase and stearoyl-CoA desaturase.
It has been predicted to be important for tissue fatty acid composition.
Recent studies suggest that inhibition of this elongase could be a new therapeutic approach for ameliorating insulin resistance, diabetes, and cardiovascular risks, even in the presence of obesity.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.