Thermo Fisher Scientific Human ELOVL6 Synthetic Peptide
인간 ELOVL6의 아미노 말단 16개 아미노산 서열에 해당하는 합성 펩타이드입니다. 항체 PA5-20520의 블로킹 펩타이드로 사용 가능합니다. 지방산 합성 연구 및 대사 관련 기전 연구에 적합합니다. 연구용으로만 사용 가능합니다.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 16 amino acids near the amino terminus of human ELOVL6.
PEP-0640 can be used as a blocking peptide with polyclonal antibody PA5-20520.
Target Information
Lipogenesis is a key event in the energy storage system and is controlled by the transcription factor sterol regulatory element-binding protein (SREBP)-1.
Elongation of very long chain fatty acids protein 6 (ELOVL6) is a member of the fatty acyl-CoA elongase gene family that converts palmitic to stearic acid and is a target of SREBP-1.
ELOVL6 plays an important role in de novo synthesis of long-chain saturated and monounsaturated fatty acids in conjunction with fatty acid synthase and stearoyl-CoA desaturase.
It has been predicted to be important for tissue fatty acid composition.
Recent studies suggest that inhibition of this elongase could be a new therapeutic approach for ameliorating insulin resistance, diabetes, and cardiovascular risks, even in the presence of obesity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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