Thermo Fisher Scientific Human RIM2 Synthetic Peptide
인간 RIM2 단백질의 중심부 17개 아미노산 서열로 구성된 합성 펩타이드입니다. 항체 PA5-20522의 블로킹 펩타이드로 사용 가능합니다. 신경전달 및 가소성 연구용으로 적합하며, PBS 완충액에 0.1% BSA와 0.02% sodium azide를 포함합니다.
- 카탈로그번호
- PEP0642
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 17 amino acids near the center of human Rim2.
PEP-0642 can be used as a blocking peptide with polyclonal antibody PA5-20522.
Target Information
Rab3-interacting molecules (RIMs) are synaptic proteins necessary for neuronal transmission and plasticity. Rim1 and Rim2 proteins are expressed in overlapping but distinct patterns throughout the brain. While the ablation of either gene was not lethal in mice, the deletion of both resulted in postnatal mortality. This lethality is due to a defect in neurotransmitter release; synapses without RIM proteins can still release neurotransmitters but are unable to do so in response to normal Ca²⁺ triggers. Like Rim1, Rim2 is thought to be an effector protein for Rab3, binding to Rab3 on synaptic vesicles in a GTP-dependent manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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