Thermo Fisher Scientific Human CADPS2 Synthetic Peptide
인간 CAPS2 단백질의 중심부 19개 아미노산 서열을 기반으로 한 합성 펩타이드. PA5-20518 항체의 블로킹 펩타이드로 사용 가능. 액상 형태, 200 µg/mL 농도, PBS(pH 7.2) 버퍼에 0.1% BSA 및 0.02% sodium azide 포함. 연구용으로만 사용.
- 카탈로그번호
- PEP0638
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific Human CADPS2 Synthetic Peptide
Applications
- Control (Ctrl): Assay-dependent
- Blocking Assay (BLOCK): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 19 amino acids near the center of human CAPS2.
PEP-0638 can be used as a blocking peptide with polyclonal antibody PA5-20518.
Target Information
CAPS2 and the related protein CAPS1 encode novel neural/endocrine-specific cytosolic and peripheral membrane proteins. Both are essential components of the synaptic vesicle priming machinery and are required for the Ca²⁺-regulated exocytosis of secretory vesicles. CAPS-deficient neurons contain no or very few fusion competent synaptic vesicles, causing a selective impairment of fast phasic transmitter release. Like CAPS1, numerous isoforms of CAPS2 are known to exist, showing distinct expression patterns in the brain. For example, CAPS2b exhibits high expression in the developing cerebellum. Furthermore, a version of CAPS2 mRNA lacking exon 3 is detected in some autistic patients, suggesting that differential expression of CAPS2 is involved in neuronal development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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