Thermo Fisher Scientific Laminin alpha-5 Monoclonal Antibody (CL3118)

Applications

Tested Dilution

Publications

Western Blot (WB)

1 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human

Published species

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

CL3118

Immunogen

Recombinant protein corresponding to Human Laminin alpha-5 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Laminin alpha-5,uniProtId:O15230-1,ncbiNodeId:9606,antigenRange:2500-2590,antigenLength:3695,antigenImageFileName:MA5-24649_Laminin_alpha-5_O15230-1_House_mouse.svg,antigenImageFileNamePDP:MA5-24649_Laminin_alpha-5_O15230-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2637264

Product Specific Information

Immunogen sequence: LNLSSIILDV NQDRLTQRAI EASNAYSRIL QAVQAAEDAA GQALQQADHT WATVVRQGLV DRAQQLLANS TALEEAMLQE QQRLGLVWAA L

Binds to an epitope located within the peptide sequence RQGLVDRAQQ as determined by overlapping synthetic peptides.

Target Information

Components of the extracellular matrix exert myriad effects on tissues throughout the body. In particular, the laminins, a family of heterotrimeric extracellular glycoproteins, affect tissue development and integrity in such diverse organs as the kidney, lung, skin, and nervous system. It is thought that laminins mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Laminins function as heterotrimeric complexes of alpha, beta, and gamma chains, with each chain type representing a different subfamily of proteins. The protein encoded by this gene belongs to the alpha subfamily of laminin chains and is a major component of basement membranes. Two transcript variants encoding different isoforms have been found for this gene, but the full-length nature of one of them has not been determined.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.