Thermo Fisher Scientific Laminin alpha-3 Monoclonal Antibody (CL3112)

Applications

Tested Dilution

Publications

Western Blot (WB)

1 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:50

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

CL3112

Immunogen

Recombinant protein corresponding to Human Laminin alpha-3 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Laminin alpha-3,uniProtId:Q16787-2,ncbiNodeId:9606,antigenRange:2002-2109,antigenLength:3333,antigenImageFileName:MA5-24648_Laminin_alpha-3_Q16787-2_House_mouse.svg,antigenImageFileNamePDP:MA5-24648_Laminin_alpha-3_Q16787-2_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2637263

Product Specific Information

Immunogen sequence: LLNRIRTWQK THQGENNGLA NSIRDSLNEY EAKLSDLRAR LQEAAAQAKQ ANGLNQENER ALGAIQRQVK EINSLQSDFT KYLTTADSSL LQTNIALQLM EKSQKEYE

Highest antigen sequence identity to the following orthologs: Mouse - 74%, Rat - 71%.

Binds to an epitope located within the peptide sequence EINSLQSDFT as determined by overlapping synthetic peptides.

Target Information

Laminin is a non-collagenous protein of basement membranes. By rotary shadowing it has a cross-like shape, consisting of one long arm, (400 kD) and three short arms (200 kD). Antibodies to laminin localize exclusively in basement membranes. Laminin is found throughout the basement membrane, but the reaction with the antibodies to laminin is more intense in the lamina lucida, the part of the basement membrane adjacent to the cell membrane. Laminin binds to type IV collagen, a component exclusively localized in the basement membrane. Laminin has been shown to play a role in cell adhesion and attachment in vivo and in vitro.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.