Thermo Fisher Scientific Laminin alpha-4 Monoclonal Antibody (CL3183)
Laminin alpha-4 단백질을 인식하는 Mouse IgG2b 단일클론 항체. WB와 IHC(P) 분석에 적합하며, 인간·마우스·랫에서 반응. Protein A로 정제된 액상 형태로, 장기 보관 시 -20°C에서 안정적 유지.
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Applications
Western Blot (WB)
- Tested Dilution: 1 µg/mL
- Publications: View 1 publication
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200–1:500
- Publications: View publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CL3183 |
| Immunogen | Recombinant protein corresponding to Human Laminin alpha-4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2637265 |
Product Specific Information
Immunogen sequence:
ENLLNQAREL QAKAESSSDE AVADTSRRVG GALARKSALK TRLSDAVKQL QAAERGDAQQ RLGQSRLITE EANRTTMEVQ QATAPMANNL TNWSQNLQHF DSSAYNTAVN SARDAVRNLT EVVPQLLDQL RTVEQKRPAS
- Highest antigen sequence identity to orthologs: Mouse - 86%, Rat - 85%
- Epitope located within peptide sequence: MANNLTNWSQNLQHF, determined by overlapping synthetic peptides
Target Information
Laminin is a non-collagenous protein of basement membranes. It has a cross-like shape consisting of one long arm (400 kD) and three short arms (200 kD). Antibodies to laminin localize exclusively in basement membranes, showing stronger reactions in the lamina lucida adjacent to the cell membrane. Laminin binds to type IV collagen, a basement membrane component, and plays a crucial role in cell adhesion and attachment both in vivo and in vitro.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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