Thermo Fisher Scientific Laminin alpha-4 Monoclonal Antibody (CL3185)
Laminin alpha-4 단백질을 인식하는 Mouse monoclonal antibody(CL3185). Western blot 및 IHC(Paraffin)에서 검증됨. Human 및 Mouse 시료에 반응하며, Protein A로 정제된 1 mg/mL 액상형 제품. 세포 부착 관련 연구용에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1 µg/mL | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:1,000 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CL3185 |
| Immunogen | Recombinant protein corresponding to Human Laminin alpha-4 (amino acids 670–809, UniProt ID: Q16363-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.0 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C for short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2637266 |
Product Specific Information
Immunogen sequence:
ENLLNQAREL QAKAESSSDE AVADTSRRVG GALARKSALK TRLSDAVKQL QAAERGDAQQ RLGQSRLITE EANRTTMEVQ QATAPMANNL TNWSQNLQHF DSSAYNTAVN SARDAVRNLT EVVPQLLDQL RTVEQKRPAS
- Highest antigen sequence identity: Mouse 86%, Rat 85%
- Recognizes an epitope within peptide sequence GALARKSALKTRLSD as determined by overlapping synthetic peptides.
Target Information
Laminin is a non-collagenous protein found in basement membranes. It has a cross-like structure with one long arm (400 kDa) and three short arms (200 kDa). Antibodies to laminin localize exclusively in basement membranes, with stronger reactivity in the lamina lucida adjacent to the cell membrane. Laminin binds to type IV collagen and plays a key role in cell adhesion and attachment both in vivo and in vitro.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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