Thermo Fisher Scientific Laminin beta-3 Monoclonal Antibody (CL3363)

Applications

Tested Dilution

Publications

Western Blot (WB)

1 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

CL3363

Immunogen

Recombinant protein corresponding to Human Laminin beta-3 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Laminin beta-3,uniProtId:Q13751-1,ncbiNodeId:9606,antigenRange:1027-1156,antigenLength:1172,antigenImageFileName:MA5-24655_Laminin_beta-3_Q13751-1_House_mouse.svg,antigenImageFileNamePDP:MA5-24655_Laminin_beta-3_Q13751-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2637270

Product Specific Information

Immunogen sequence: KLVTSMTKQL GDFWTRMEEL RHQARQQGAE AVQAQQLAEG ASEQALSAQE GFERIKQKYA ELKDRLGQSS MLGEQGARIQ SVKTEAEELF GETMEMMDRM KDMELELLRG SQAIMLRSAD LTGLEKRVEQ

Highest antigen sequence identity to the following orthologs: Mouse - 75%, Rat - 76%.

Binds to an epitope located within the peptide sequence MTKQLGDFWTRMEEL as determined by overlapping synthetic peptides.

Target Information

The product encoded by this gene is a laminin that belongs to a family of basement membrane proteins. This protein is a beta subunit laminin, which together with an alpha and a gamma subunit, forms laminin-5. Mutations in this gene cause epidermolysis bullosa junctional Herlitz type, and generalized atrophic benign epidermolysis bullosa, diseases that are characterized by blistering of the skin. Multiple alternatively spliced transcript variants that encode the same protein have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.